Nuvera’s One Big Beautiful PlaybookBy: Corey Ford, Principal, Nuvera
Ready for O3B?
Safeguard Your Patient Support Program for 2027 and Beyond
The One Big Beautiful Bill, or O3B and OBBB, is expected to reshape the healthcare landscape, especially the Medicaid program, driving access and affordability challenges for patients.
As the new law exacerbates patient access challenges with coverage losses and overall confusion, patient support programs need to prepare now for the operational, strategic, and financial impact on their patient services ecosystems.
Download Nuvera’s One Big Beautiful Playbook
to understand how O3B may affect your patient populations and learn a practical, cross-functional framework for preparing your organization for 2027 and beyond.
Why This Playbook Matters Now
In an already chaotic policy landscape, O3B is driving greater complexity for patient access. Policy changes tied to O3B may increase coverage instability, create new affordability challenges, and place additional pressure on patient services teams already managing complex treatment journeys.
For pharmaceutical, biotech, and life sciences organizations, the impact may extend across:
- Medicaid enrollment and eligibility workflows
- Insurance coverage verification and reverification
- Financial assistance program (e.g. patient assistance, bridge program, and even copay assistance) demand
- Forecasting, budgeting, and program capacity planning
- Hub, field reimbursement, and access team operations
- Patient and HCP/office education and outreach
Nuvera’s playbook helps patient services leaders tackle uncertainty through action via a practical roadmap for assessing risk, aligning stakeholders, and deploying program changes before patients experience disruption in 2027.
Who Should Download This Playbook?
This resource is built for leaders responsible for protecting patient access and optimizing support programs in a changing policy environment, including:
- Patient Services Leaders
- Market Access Teams
- Patient Support Program Directors
- Commercial and Brand Leaders
- Field Reimbursement and Access Teams
- Hub and Access Operations Leaders
- Affordability and Patient Assistance Program Teams
- Life Sciences Strategy and Planning Teams
A Practical Framework for
Patient Access Leaders
Nuvera’s One Big Beautiful Playbook is designed to help life sciences organizations prepare for OBBB through a structured, action-oriented framework.
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Phase 1:
Gauge the ImpactUnderstand how O3B may affect your patient population(s), financial assistance program demand, and stakeholder education needs.
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Phase 2:
Build Your StrategyAlign patient services, market access, brand, commercial, legal, compliance, and field teams around the operational and financial decisions required to support patients through disruption.
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Phase 3:
Deploy Program ChangesTranslate strategy into action across patient support programs, PAPs, copay offerings, hub workflows, field reimbursement models, stakeholder engagement, and performance measurement.
What You’ll Learn
- How OBBBA policy changes may impact patient access, coverage continuity, and affordability
- What increased uninsured and underinsured rates could mean for free drug, PAP, bridge, and copay programs
- Where patient support teams may experience greater operational pressure
- How the complexity of the changes will drive stakeholder confusion around coverage options and available patient support
- A three-phase roadmap to assess impact, build strategy, and deploy program changes
Why Nuvera?
Nuvera Life Science Consulting helps pharmaceutical and biotech organizations uncover patient and HCP needs, design support experiences, and reduce barriers across the treatment journey. As O3B introduces new access and affordability pressures, Nuvera helps life sciences teams assess risk, adapt support models, and protect the patient experience.
Is your patient support program ready for O3B?
Coverage disruption, financial need, and questions from program users a may accelerate as O3B-related changes take effect. The organizations that prepare now will be better positioned to support patients, reduce program strain, and make informed access decisions for 2027 and beyond.